Abstract #1812

Dependence of PDFF Measurement Accuracy on Location, Resolution, and Field Strength – a Phantom Experiment

Nikolaos Panagiotopoulos^1,2, David Rutkowski³, Alexandra Anagnostopoulos¹, Thekla H Oechtering^1,2, Diego Hernando^1,3,4,5,6, Jean Brittain³, and Scott B Reeder^1,3,4,5,7,8

¹Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ²Department of Radiology and Nuclear Medicine, Universität zu Lübeck, Lübeck, Germany, ³Calimetrix, Madison, WI, United States, ⁴Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁵Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁶Department of Departments of Electrical & Computer Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁷Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁸Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Quantitative Imaging, Phantoms

The purpose of this work was to determine the spatial dependence of PDFF measurements at both 1.5T and 3.0T in a phantom setting. We showed that bias in CSE-MRI-based PDFF measurements is low when performed in areas not more than 20 cm from the isocenter in any direction. These results have immediate practical relevance for clinical routine, e.g., in prescribing MRI acquisitions for clinical PDFF measurements and for the correct placement of pocket phantoms in the MRI bore when used as quality assurance tools.

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