Abstract #1844

Evaluation the value of T1rho and Gd-EOB-DTPA-Enhanced T1 Mapping for liver function reserve in patients with chronic liver disease

Jie Zou^1,2,3, Yanli Jiang^1,2,3, Fengxian Fan^1,3, Pin Yang^1,3, Yuan Ding^1,3, Jing Zhang^1,3, Kai Ai⁴, and Zhigang Wu⁵

¹Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China, ²Second Clinical School, Lanzhou University, Lanzhou, China, ³Gansu Province Clinical Research Center for Functional and Molecular Imaging, Lanzhou, China, ⁴Philips Healthcare, Xi'an, China, ⁵Philips Healthcare, Shenzhen, China

Synopsis

Keywords: Liver, Liver, T1rho, chronic liver disease, T1 mappingThe purpose of this study is to evaluate the diagnostic performance of T1 rho and Gd-EOB-DTPA-Enhanced T1 Mapping in patients with chronic hepatitis B in liver function reserve. For the two groups of Child-Pugh A vs. B/C and Child-Pugh A/ B vs. C, the AUC of T1 rho and T1_post-10min is higher than other metrics. The AUC value combined with these two indicators is the highest (0.861; 0.912). Δ T1, Δ R1 and ECV and T1 rho quantitative techniques may be helpful for staging liver function reserve, and the combination of T1 rho and T1_post-10min can provide higher diagnostic efficiency.

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