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Abstract #1859

Prognostic Value of ADC Histogram Analysis in Men with High Risk Prostate Cancer Receiving Adjuvant Hormonal Therapy after Radical Prostatectomy

Kangwen He1, Xiaoyan Meng1, and Zhen Li1
1Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Synopsis

Keywords: Prostate, Cancer, high-risk prostate cancer, biochemical recurrence直方图分析是医学图像的定量后处理方法,被认为在癌症管理中很有价值。我们使用表观扩散系数 (ADC) 图的直方图参数分析了在根治性前列腺切除术 (RP) 后接受辅助激素治疗 (AHT) 的高危前列腺癌 (PCa) 患者的结果。我们观察到,较低的 ADC 50 和较高的峰度可以独立预测较差的生化无复发生存期 (BCR-fs),并且当添加直方图参数时,预后模型的性能会有所提高。我们的研究结果显示了 ADC 直方图分析在这一特定的 PCa 患者亚组中的增量预后价值。

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Keywords