Meeting Banner
Abstract #1867

Studying variation in DWI MRI derived ADC for Prostate Cancer (PCa) with respect to Gleason Grade and location of PCa lesions

Sudhanya Chatterjee1, Dattesh Dayanand Shanbhag1, Aanchal Mongia1, Uday Patil1, Adele Courot2, Nicolas Gogin2, and Rakesh Mullick1
1GE Healthcare, Bangalore, India, 2GE Healthcare, Buc, France

Synopsis

Keywords: Prostate, Cancer, DWI, ADC, Gleason gradeDiffusion weighted MRI (DWI) derived apparent diffusion coefficient (ADC) is a marker of the extent of restrictive diffusion in tissues. Higher Gleason Grade (GG) prostate cancer (PCa) lesions are known to exhibit higher restrictive diffusion. In this study we investigated whether ADC as a tissue biomarker follows the known histopathological behavior of PCa lesions by studying variations in ADC with respect to GG of PCa lesions and its location. We observe that ADC values of lesion voxels, although belonging to same GG, vary based on its location.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords