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Abstract #1910

Repeatability of Quantitative Measures in Long COVID using Hyperpolarized 129Xe MRI

Keegan Staab1, Jonathan Percy2, Andrew D. Hahn3, Stanley J. Kruger3, Alejandro P. Comellas4, Jessica C. Sieren3, Eric A. Hoffman3, and Sean B. Fain3
1Biomedical Engineering, University of Iowa, Iowa City, IA, United States, 2Physics, University of Iowa, Iowa City, IA, United States, 3Radiology, University of Iowa, Iowa City, IA, United States, 4Internal Medicine, University of Iowa, Iowa City, IA, United States

Synopsis

Keywords: Lung, COVID-19Repeatability visits with hyperpolarized 129Xe MRI of ventilation and gas exchange measures were acquired at baseline and 3-6 weeks after baseline in patients with persistent dyspnea, fatigue, and neurocognitive symptoms (“Long” COVID). Findings did not support the same repeatability of measures found in a previous study of IPF, suggesting instability of pulmonary pathophysiology is a characteristic of Long COVID.

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