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Abstract #1911

Evident Cerebral Perfusion Recovery in COVID-19 Patients: Results Based on Arterial Spin Labeling MRI

Yu Shen1,2, Xianchang Zhang3, Yaping Wu1,2, Yan Bai1,2, Wei Wei1,2, Lijuan Chen1,2, and Meiyun Wang1,2
1Department of Medical Imaging, Henan Provincial People’s Hospital & Zhengzhou University People’s Hospital, Zhengzhou, China, 2Henan Key Laboratory of Neurological Imaging, Zhengzhou, China, 3MR Collaboration, Siemens Healthcare Ltd, Beijing, China

Synopsis

Keywords: Neuroinflammation, COVID-19, perfusion,follow upCOVID-19 may affect the brain of patients, ranging in severity from confusion to life-threatening strokes. This study investigated the potential cerebral perfusion change in COVID-19- infected patients using pseudo-continuous arterial spin labeling (pCASL) sequence by follow up after patients recovered for 4, 12 and 18 months. It’s found that both cerebral blood flow (CBF) and bolus arrival time (BAT) values derived from pCASL demonstrated an increasing tendency over time in several brain areas in COVID-19 survivors after whole brain analysis. Our findings indicated that COVID-19 survivors may experience compensatory brain function recovery and this recovery process would be slow.

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