Abstract #1940

Evaluation of Brain Iron Deposition in Different Cerebral Artery of Acute Ischemic Stroke by using Quantitative Susceptibility Mapping

Jie Yang¹, Jianquan Zhong¹, Minli Lv¹, Yan Li ¹, Limei Han^1,2, Hao Feng¹, Chaoliang He^1,3, Chunyan Zheng¹, Zhejun Wang¹, and Yunzhu Wu⁴

¹Department of Radiology, Zigong First People's Hospital, Zigong, China, ²North Sichuan Medical College, Nanchong, China, ³Sichuan Vocational College of Health and Rehabilitation, Zigong, China, ⁴MR Scientific Marketing, SIEMENS Healthineers Ltd., Shanghai, China

Synopsis

Keywords: Stroke, Blood vessels, Iron DepositionIn this study, QSM was used to investigate susceptibility differences among infarct region, non- infarct regions of responsible artery and non-responsible artery in acute ischemic stroke (AIS) patients. The results showed that only susceptibility of the infarct region was significantly higher than that of healthy controls. In AIS patients, the susceptibility of infarct region were significantly higher than those of normal cerebral artery regions and non-infarction regions of responsible artery. These results suggest that abnormal iron deposition exists in the infarct region and may not affect other non-infarct regions.

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