Abstract #1950

Therapeutic Efficacy of Extracellular Vesicles from 3D Aggregated Adult Human Mesenchymal Stem Cells for Ischemic Stroke Assessed by MRI at 21.1 T

Jamini Bhagu^1,2 and Samuel Colles Grant^1,2

¹National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, United States, ²Chemical & Biomedical Engineering, FAMU-FSU College of Engineering, Tallahassee, FL, United States

Synopsis

Keywords: Stroke, Non-Proton, sodium, MCAOThis study evaluates the therapeutic efficacy of transplanted extracellular vesicles (EV) secreted from 3D aggregated human mesenchymal stem cells to treat transient ischemic stroke in a female rat model. The objective is to verify the presence of EV at the lesion and monitor tissue recovery using T₂- and diffusion-weighted MRI at 21.1 T.

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