Abstract #1965

Histogram analysis based on T2 mapping can predict the molecular markers in meningiomas

Zongye Li¹, Yijie Yang², Yue Zhang¹, Yanhong Lin², Xiao Wang¹, Yuchuan Zhuang³, Qinqin Yang², Eryuan Gao¹, Yanan Ren¹, Yong Zhang¹, Shuhui Cai², Zhong Chen², Congbo Cai², Jingliang Cheng¹, and Jianfeng Bao¹

¹Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²Department of Electronic Science, Xiamen University, Xiamen, China, ³Department of Imaging Sciences, University of Rochester, Rochester, NY, United States

Synopsis

Keywords: Tumors, Relaxometry

There is an immediate need for neurosurgeons to be able to identify certain molecular markers’ status of meningioma preoperatively, such as progesterone receptors and S100. In this study, we explored the use of histogram analysis of T2 maps and ADC maps in predicting such molecular markers. T2 maps and ADC maps could serve as useful tools for predicting PR and S100 status of meningiomas. Similar studies may be extended to investigate other pathological markers.

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