Abstract #1970

Glioma grading using multiparametric MRI: head-to-head comparison among four different advanced techniques

Minkook Seo¹, Yangsean Choi¹, Youn Soo Lee², Kook-Jin Ahn¹, Bum-soo Kim¹, Jae-Sung Park³, and Sin-soo Jeon³

¹Radiology, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Hospital Pathology, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ³Neurosurgery, Seoul St. Mary's Hospital, Seoul, Korea, Republic of

Synopsis

Keywords: Tumors, Tumor, GliomaDiagnostic performances differentiating low-grade (LGGs) from high-grade gliomas (HGGs) were compared between the four advanced techniques of multiparametric MRI—DSC, DCE, MRS and DWI. Sixty-four patients with pathologically confirmed glioma underwent preoperative multiparametric MRI with the four techniques, followed by histogram analysis of the tumors. HGGs showed significantly higher K^trans, rCBV, and Cho/Cr than LGGs. The AUROC of the 95th percentile K^trans was 0.83, being the most helpful parameter, followed by 95th percentile rCBV (0.72). Significant correlations were observed between the 95th percentile rCBV and K^trans. Our findings demonstrate higher diagnostic utility of DCE and DSC MRI in glioma grading.

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