Abstract #1974

Correlation of MRI Radiomics Features and Recurrence After Gamma Knife Treatment in Parasagittal and Falx Meningiomas

Esra Sümer¹, O Artunç Türe², Meriç Şengöz^3,4, M Necmettin Pamir^3,4, Alp Dinçer^4,5, Koray Özduman^3,4, and Esin Ozturk-Isik^1,4

¹Institute of Biomedical Engineering, Boğaziçi University, İstanbul, Turkey, ²Department of Radiation Oncology, Acıbadem University, İstanbul, Turkey, ³Department of Neurosurgery, Acıbadem University, İstanbul, Turkey, ⁴Brain Tumor Research Group, Acıbadem University, İstanbul, Turkey, ⁵Department of Radiology, Acıbadem University, İstanbul, Turkey

Synopsis

Keywords: Tumors, Radiomics, Gamma Knife, meningiomaMeningiomas located at and around the falx and superior sagittal sinus are known to have a more aggressive clinical behavior. Additionally, their localization and invasion characteristics make complete resection difficult, creating a need for radiosurgery. This study assessed the relationship between radiomics/clinical features of parasagittal and falx meningiomas and their recurrence-free survival after Gamma Knife. The radiomics and clinical features (age, pre-op tumor volume, coverage, and sensitivity) were analyzed together. Univariable Cox analysis associated maximum and skewness of T1 lesion, age, TV, and coverage, whereas multivariable Cox analysis associated skewness of T2 lesion, coverage, and selectivity with RFS.

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