Abstract #2024

Initial observations and potential pitfalls when validating respiratory correlated MRI for radiotherapy planning.

Evanthia Kousi¹, Joan Chick¹, Andreas Wetscherek¹, Julie Hughes², Georgina Hopkinson², Jessica Gough^2,3, Rosalyne Westley^2,3, Radhouene Neji⁴, Simeon Nill¹, Dow-Mu Koh^2,3, and Uwe Oelfke¹

¹Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom, ²The Royal Marsden NHS Foundation Trust, London, United Kingdom, ³The Institute of Cancer Research, London, United Kingdom, ⁴MR Research Collaborations, Siemens Healthcare, Frimley, United Kingdom

Synopsis

Keywords: Data Analysis, Radiotherapy, 4D-MRI, Respiratory correlated MRI, radiotherapy planning

In this abstract we present our initial results from the validation of a respiratory correlated 4D MRI golden angle stack of stars radial sequence prior to its clinical implementation and highlight potential experimental pitfalls to avoid that may impact motion range estimations.

Correct phantom set up reduced motion underestimations by 3%-18% for the simulated respiratory waveforms considered. Larger motion discrepancies observed for the low amplitude motion which improved by increasing the number of bins.

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