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Abstract #2026

A nomogram based on DKI, molecular and clinical risk factors for survival prediction and treatment decision-making in astrocytomas

Yan Tan1, Zeliang Liu2, Xiaochun Wang1, and Hui Zhang1
1First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China, China, 2LinFen People's Hospital, Linfen, Shanxi Province, China, China

Synopsis

Keywords: Data Analysis, Tumor, diffusion kurtosis imaging, nomogram, astrocytoma, overall survival, treatmentTo establish a nomogram by integrating DKI, molecular and clinical risk factors for personalized OS estimation in astrocytomas, and explore the nomogram-based treatment benefits. Astrocytomas are the most common brain tumors with poor prognoses. The detection of risk factors may aid in individualizing therapeutic plans and improve survival. It is concluded the nomogram based on DKI, molecular and clinical risk factors could achieve the individualized OS estimation of astrocytomas with excellent performance. For high-risk patients, surgery plus chemo and/or radiotherapy were recommended; while for low-risk patients, additional chemo and/or radiotherapy did not increase survival benefits.

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Keywords