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Abstract #2043

Evaluating liver fibrosis in chronic hepatitis B patients using multi-compartment restriction spectrum imaging

Jing Zhang1, Kaifan Yang1, Yiyuan Zhu1, Liyun Zheng2, Yongming Dai3, and Yikai Xu1
1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 2Shenzhen United Imaging Research Institute of Innovative Medical Equipment, Shenzhen, China, 3MR Collaboration, Central Research Institute, United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Liver, Diffusion/other diffusion imaging techniquesThis study evaluated the feasibility of the restriction spectrum imaging (RSI) model in the characterization and staging of liver fibrosis. The results demonstrated that the four-compartment model emerged as the best option and the C4 derived from the four-compartment model outperformed conventional apparent diffusion coefficient (ADC) values. Therefore, the four-compartment RSI model could be a noninvasive and in vivo diagnostic technique in the evaluation of chronic hepatitis, which is conducive to treatment decisions and patient management.

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