Abstract #2050

Simulation of Short Breath-hold Steady State MultiParameter MRS in Liver.

Gavin Hamilton¹, Walter C Henderson¹, Danielle N Batakis¹, Lael Ceriani¹, Ashley L Louie¹, Yesenia Covarrubias¹, Celene Gonzalez¹, Michael S Middleton¹, Scott B Reeder², Kathryn J Fowler¹, and Claude B Sirlin¹

¹Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, United States, ²Department of Radiology, University of Wisconsin, Madison, Madison, WI, United States

Synopsis

Keywords: Liver, SpectroscopyTo permit simultaneous T1w, T1f, T2w, T2f and proton density fat fraction (PDFF) estimation, we developed a single-average, 21 s, single-breath-hold, Steady-state, Multi-Parameter MRS (SMP MRS) sequence. However, a 21 s breath-hold may be challenging especially children, such as pediatric subjects, so we simulated a shorter 12 s breath-hold sequence by removing the longer TR and TE values. We found good agreement for T1w, T2w and PDFF between the full 21 s SMP and simulated 21 s sequences, suggesting the shorter 12 s SMP MRS can be run instead of the full 21 s sequence.

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