Abstract #2052

Association Between NAFLD and Blood Flow: Portal 4D-flow, 2D-flow, Hepatic Elasticity and Spleen Volume

Jonatan Eriksson^1,2, Wolf Bartholomä^2,3, Nils Dahlström^2,3, Jens Tellman^1,2, Stergios Kechagias⁴, Patrik Nasr⁴, Mattias Ekstedt^2,4, Johan Kihlberg^2,3, and Peter Lundberg^1,2

¹Department of Medical Radiation Physics, and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden, ²Center for Medical Imaging Science and Visualization, Linköping University, Linköping, Sweden, ³Department of Radiology in Linköping and Department of Health Medicine and Caring Sciences, Linköping University, Linköping, Sweden, ⁴Division of Diagnostics and Specialist Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden, Linköping, Sweden

Synopsis

Keywords: Liver, Blood vessels, 4D Flow, 2D Flow, MRE, Spleen

A group of 6 healthy and 9 NAFLD-patients underwent a multi-parametric MRI examination, including 4D-, 2D-flow, MRE and relaxometry. 2D-flow results were successfully extracted from 4D-flow data, showing good match with 2D-flow, indicating that 4D-flow provides the opportunity to both provide regular flow values as well as additional information e.g. flow visualizations. Correlation between 4D-flow and spleen volume indicate that 4D-flow could provide markers for early portal hypertension.

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