Abstract #2071

3D Distortionless Diffusion Weighted Imaging in the Prostate using a Diffusion Prepared Fast Spin-Echo Sequence

Jeremiah Joseph Hess¹, Philip Kenneth Lee², Xuetong Zhou¹, Andreas Markus Loening², and Brian Andrew Hargreaves^1,2,3

¹Bioengineering, Stanford University, Stanford, CA, United States, ²Radiology, Stanford University, Stanford, CA, United States, ³Electrical Engineering, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Prostate, Diffusion/other diffusion imaging techniquesDiffusion-Weighted Imaging (DWI) of the prostate is commonly used for tumor detection and characterization. However, the echo planar imaging (EPI) based DWI methods commonly used in prostate imaging fail in the setting of field inhomogeneities most related to hip prosthesis and rectal gas. Cartesian Fast Spin-Echo (FSE) is an alternative to EPI that is more robust to off-resonance. In this study, we compare in vivo 3D FSE to multi-shot EPI (MUSE) for DWI prostate imaging, demonstrating that an FSE DWI sequence achieves high image quality while avoiding geometric distortion seen in EPI based DWI.

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