Abstract #2078

Feasibility of textural analysis and very-low-field magnetic resonance for imaging Nipah virus infection

Kunal Aggarwal^1,2, Yu Cong³, Ji Hyun Lee⁴, Venkatesh Mani³, Claudia Calcagno⁵, Michael R. Holbrook⁵, and Sairam Geethanath⁶

¹Department of Electrical and Computer Engineering, Technical University Munich, Munich, Germany, ²Deptartment of Diagnostic, Molecular and Interventional Radiology, Mount Sinai Hospital, New York City, NY, United States, ³National Institute of Allergy and Infectious Diseases, Fort Detrick, MD, United States, ⁴Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, United States, ⁵National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, MD, United States, ⁶Mount Sinai Hospital, New York, NY, United States

Synopsis

Keywords: Infectious disease, Infectious diseaseOur study focuses on textural analysis of high field and low field MR images and its validation through simulation. We acquired MR images of three NHPs at 3T injected with NiV and simulated them into low field to perform texture analysis for different neuroanatomies. The low field simulation was done by changing contrast, resolution and SNR. The validation of low field simulation was performed by scanning phantom at 3T and 0.05T and passing the data though low field simulator. Results showed four out of 14 textural features had similar changes in 2 NHPs.

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