Abstract #2098

T2 Mapping in Hemorrhagic and Ischemic Stroke using Standard Clinical Images

Ashmita De¹, Jeff Snyder¹, Mahesh Kate², Derek J. Emery³, and Alan H. Wilman¹

¹Department of Biomedical Engineering, University of Alberta, Edmonton, AB, Canada, ²Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB, Canada, ³Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada

Synopsis

Keywords: Stroke, BrainT2 mapping can provide a route to monitor both iron changes in hemorrhage and water changes in ischemic stroke. Our aim is to investigate the value of T2 mapping from standard proton density and T2-weighted fast spin echo images for hemorrhagic and ischemic stroke. Rapid T2 maps using sequence modeling were reconstructed and compared with susceptibility and apparent diffusion coefficient for 13 hemorrhages and 14 ischemic stroke lesions respectively. Quantitative T2 is highly correlated with susceptibility for hemorrhage and diffusion for ischemic stroke, providing complementary measurements of water and iron changes.

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