Abstract #2107

Identification of intracranial atherosclerotic plaque features associated with recurrent stroke: a multi-modality imaging study

Lingling Wang¹, Beibei Sun¹, Maysam Orouskhani², Mahmud Mossa-Basha², Jianrong Xu¹, Yan Zhou¹, Chengcheng Zhu², and Huilin Zhao¹

¹Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, ²University of Washington, Seattle, United States, Seattle, WA, United States

Synopsis

Keywords: Stroke, Atherosclerosis, CalcificationIntracranial atherosclerotic plaque is a major cause of stroke. Both CTA and vessel wall magnetic resonance imaging (VW-MRI) can identify high risk plaque features. We aim to investigate the intracranial atherosclerotic plaque features associated with recurrent stroke using a multi-modality imaging approach by combining CTA and whole brain VW-MR. We found that higher calcium burden quantified by volume and Agatston score of intracranial arteries, as well as whole-brain plaque number and culprit plaque burden were independently associated with recurrent acute stroke.

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