Abstract #2112
Following evolving pH changes in the penumbra using a novel MRI method
Eleni Demetriou1,2, Valerie Taylor3, Mohamed Tachrount4, Kimmo Jokivarsi 5, Olli Grohn5, Rolf Jager6, Karin Shmueli7, and Xavier Golay8
1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 2Brain repair and Rehabilitation, Institute of Neurology, Dallas, TX, United States, 3University College of London, Center for Advanced Biomedical Imaging, London, United Kingdom, 4Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, London, United Kingdom, 5A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland, Kuopio, Finland, 6Institute of Neurology, Brain repair and rehabilitation, London, United Kingdom, 7Department of Medical Physics & Bioengineering, University College London, UK, London, United Kingdom, 8Brain repair and rehabilitation, Institute of Neurology, London, United Kingdom
Synopsis
Keywords: Stroke, Ischemia, ischemic penumbraHere, our goal was to visualise dynamic pH changes in a rat model of MCAO and their relation to other imaging techniques for identifying the penumbra zone which is used to guide therapeutic intervention.
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