Keywords: Adolescents, Kidney
Blood oxygen level dependent magnetic resonance imaging (BOLD-MRI) could be used to detect renal tissue oxygen levels noninvasively, and the T2* time induced by the paramagnetic effect of deoxyhemoglobin can be obtained to indirectly assess blood oxygen utilization. Previous research has proven that BOLD-MRI can detect renal oxygenation levels with high sensitivity and the accuracy of the data has been validated by invasive probe measuring techniques. In this work, we investigated the clinical feasibility of T2* mapping for the detection of HSPN and HSP in children, since we predicted that HSPN would also result in aberrant renal blood oxygenation signals.
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