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Abstract #2163

Parallel transmit (pTx) kT-points pulses improve 500µm resolution quantitative multi-parameter mapping (MPM) at 7T

Kerrin J Pine1, Nicolas Groß-Weege1,2, Luke J Edwards1, Tobias Leutritz1, Patrick Freund1,3, and Nikolaus Weiskopf1,4
1Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 2Siemens Healthcare GmbH, Erlangen, Germany, 3Spinal Cord Injury Center Balgrist, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 4Felix Bloch Institute for Solid State Physics, Faculty of Physics and Earth Sciences, Leipzig University, Leipzig, Germany

Synopsis

Keywords: Quantitative Imaging, Parallel Transmit & Multiband, NeuroQuantitative multi-parameter mapping (MPM) at 7T can provide detailed information about brain microstructure. However, it is limited by B1+ radio-frequency (RF) transmit field inhomogeneities leading to bias and dropouts. We implemented a kt-points RF pulse approach in 500µm resolution multi-echo spoiled GRE acquisitions and AFI B1+ mapping used for MPM. It was optimized for a homogeneous non-selective excitation with short RF pulse durations, SAR compliance and high usability. In a group of 8 volunteers, bias and shading artifacts were significantly reduced. The approach is integrated in the routine scanning workflow, improving whole brain ultra-high resolution MPM at 7T.

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