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Abstract #2167

Efficient fetal brain and placental T1 mapping at 0.55T

Jordina Aviles Verdera1,2, Raphael Tomi-Tricot1,2,3, Lisa Story1,4, Joseph V Hajnal 1,2, Mary A Rutherford1,2, Shaihan Malik1,2, and Jana Hutter1,2
1Center for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom, 2Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom, 3MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 4Women's Health, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom

Synopsis

Keywords: Quantitative Imaging, Low-Field MRIFetal MRI provides crucial anatomical and functional information. At low field it could benefit from reduced distortion, increased bore size and increased B1 homogeneity. T1 contrast and mapping in the fetal brain provides complementary information for example for haemorrhages, infarcts and in placental disease. Here, a low-field (0.55T) fetal T1 inversion-recovery EPI-based sequence benefiting from the lower T1 and hence higher efficiency is demonstrated for placenta and brain in a cohort of pregnant participants including two clinical cases. Significant correlation with gestational age is demonstrated (p<0.05) and high quality maps allowing sub-regions analysis in the brain are shown.

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Keywords