Abstract #2169

Three-dimensional black-blood T1 mapping of arterial plaque and venous thrombosis: a concept-proof study

Yuhui Nie¹, Zeping Liu¹, Anyan Gu¹, Liping Liao², Qizeng Ruan², Zehe Huang², Yi Sun³, and Guoxi Xie¹

¹School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, China, ²The First People’s Hospital of Qinzhou, Qinzhou, China, ³Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China

Synopsis

Keywords: Quantitative Imaging, Cardiovascular, T1 mappingQuantitative T1 mapping have showed the potential to characterize arterial plaque and venous thrombotic components. However, owing to the interference of blood signals, it is a challenge for T1 mapping technique to combine with black-blood imaging, which may otherwise be a confounder for plaque and thrombus component. In this study, we present a black-blood T1 mapping technique based on DANTE black-blood preparation and MP2RAGE sequence. Experiment results demonstrated that BB-MP2RAGE provided accurate measurement of T1 relaxation time with effective blood suppression. The technique has the potential to be a quantitative tool for thrombosis and plaque characterization.

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