Abstract #2173

Glymphatic system abnormality in systemic lupus erythematosus identified by diffusion tensor image analysis along the perivascular space

Jiaying Mo¹, Kan Deng², Xiangliang Tan¹, and Yikai Xu¹

¹Department of Medical Imaging Center, Nanfang Hospital of Southern Medical University, Guangzhou, China, ²Philips Healthcare, Guangzhou, China

Synopsis

Keywords: Head & Neck/ENT, Brain, Systemic lupus erythematosus

DTI-ALPS is an non-invasive method to measure glymphatic clearance function in brain. Here, we aimed to utilize DTI-ALPS to evaluate the activity of glymphatic system and explore its relationship with grey matter volumes in patients with SLE. Our results demonstrated that the ALPS-index are lower in SLE patients than that in healthy control group. And there were significant correlations between lower ALPS-index and smaller gray matter volumes in some brain regions in SLE group.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.