Keywords: Tumors, Endocrine, Diffusion Tractograpy, hypothalamusHere we outline a preliminary analysis using a novel method that leverages UHF neuroimaging to measure detectable differences in volumetric, microstructural and tractographic measures in the hypothalamus in patients with pituitary tumors and matched controls. We uncovered significant detectable volumetric and differences within five hypothalamic subnuclei, and the whole left hypothalamus. We observed subtle differences in microstructural integrity, and although not statistically significant warrant further investigations in a larger cohort of pituitary adenoma patients. This may also facilitate exploration of microstructural integrity within other tumor types that may have effects on the hypothalamus.
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