Abstract #2180

Magnetisation Transfer effects on T1 and T2 values in MR Fingerprinting

Simran Kukran^1,2, Iulius Dragonu³, Ben Statton^1,4, Jack Allen⁵, Pete Lally^1,6, Rebecca Quest^1,7, Neal Bangerter¹, Dow-Mu Koh², Matthew Orton², and Matthew Grech-Sollars⁸

¹Imperial College London, London, United Kingdom, ²Institute of Cancer Research, London, United Kingdom, ³Siemens Healthcare Ltd, Frimley, United Kingdom, ⁴London Institute of Medical Sciences, Medical Research Council, London, United Kingdom, ⁵Independent Researcher, Norwich, United Kingdom, ⁶UK Dementia Research Institute Centre for Care Research and Technology, London, United Kingdom, ⁷Imperial College Healthcare NHS Trust, London, United Kingdom, ⁸University College London, London, United Kingdom

Synopsis

Keywords: MR Fingerprinting/Synthetic MR, Magnetization transferA fingerprinting sequence was developed with and without off resonance pulses before every TR to investigate MT effects on T1 and T2 values. Off-resonance pulses suppress MT effects by saturating signal from free protons that exchange with bound protons. Observed T2 values increased with off resonance pulses as expected. Observed T1 values decreased, this was an opposite effect to what was observed previously with a different pulse sequence.

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