Keywords: MR Fingerprinting/Synthetic MR, Quantitative Imaging, Reproducibility, MNI, Automated, Gadgetron, FIREWe evaluate the reproducibility of 3D-MRF versus clinical-standard MPRAGE and TSE acquisitions for ten subjects across three acquisition sets on two scanner via a fully-automated registration and regional analysis framework. T1 and T2 quantitative maps from 3D-MRF were found to be highly reproducible (T1+/-4.6%, T2+/-6.3%) across scanners and sessions, with no significant difference between repeating a scan immediately on the same scanner, repeating a scan after repositioning the subject and reshimming, and repeating a scan on a different scanner entirely. The same is not true for MPRAGE (+/-12.4%) or TSE (+/-28.8%) acquisitions.
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