Keywords: Image Reconstruction, Quantitative ImagingAny MRI practices prefer high resolution, high signal-to-noise ratio, short scan time, and high contrast. Unfortunately, fast scan leads to low resolution while high-resolution scan results in a reduced signal-to-noise ratio. In particular, it is challenging for radiologists and technologists, who perform MRI scans, to find optimal sequence parameters for each patient, leading to sub-optimal contrast. We developed a new methodology that enables fast and high-resolution brain MRI with improved signal-to-noise ratio and optimal contrast between white-matter and gray-matter for each individual patient, based on quantitative imaging and reconstruction techniques. Experiments on clinical data demonstrated the advantages of our approach.
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