Abstract #2220

Ex vivo lymph node staging by a portable low-field MRI scanner

Anke Christenhusz¹, Frank F.J. Simonis¹, Bennie ten Haken¹, Justin C.A. te Wildt¹, Sadaf Sadamzadeh¹, Anneriet E. Dassen², and Lejla Alic¹

¹Magnetic Detection and Imaging, University of Twente, Enschede, Netherlands, ²Surgery, Medisch Spectrum Twente, Enschede, Netherlands

Synopsis

Keywords: Data Acquisition, Cancer, Lymph node, low-field, portable scannerSentinel lymph node (LN) biopsy facilitated by magnetic nanoparticles (MNP) is introduced for breast cancer patients eligible for breast conserving surgery. As m1etastatic depositions potentially introduce changes in heterogeneity of MNP-enhanced MRI, a portable low-field MRI scanner can be used for ex vivo perioperative LN staging. Therefore, we assessed the changes in T1w, T2w and STIR images due to iron deposition in LN. 2Clinically relevant LN segments, such as fat and iron depositions, identified in the pathology images, were also observable in MR scans.

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