Abstract #2223

A Frequency Modulation HArd Pulse ENcoding Sequence for Ultra-Short Echo Time High-Resolution Three-Dimensional MR Imaging

Jun Zhao^1,2, Yupeng Cao¹, Weinan Tang³, Quelu Chen⁴, Wentao Liu¹, and Dong Han¹

¹Key Laboratory of Biological Effects and Safety, National Center for Nanoscience and Technology, beijing, China, ²School of Future Technology, University of Chinese Academy of Sciences, Beijing, China, ³Wandong Medical Inc, Beijing, China, Beijing, China, ⁴Department of Radiology, Wenzhou Central Hospital, Affiliated Dingli Clinical Institute of Wenzhou Medical University, Wenzhou, China

Synopsis

Keywords: Pulse Sequence Design, Lung, hard pulse encoding, variable TE, frequency modulation, spiralDue to its short T₂^* value and low proton density, MR imaging of the lung is quite challenging. Recently, ultra-short echo time (UTE) techniques, such as stack-of-spiral, were used to conduct lung MRI with good image quality. Here, based on stack-of-spiral, a frequency modulation hard pulse encoding (HAPEN) 3D UTE was proposed to optimize the echo time of different phase encoding steps in the slice direction. As a result, HAPEN can achieve shorter TE and get better SNR in human lung MRI compared to the traditional stack-of-spiral UTE sequence.

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