Meeting Banner
Abstract #2250

Development of Hepatocellular Carcinoma phantom and its use for assessing R2* mapping sequences for detecting iron sparing

Elisabeth Pickles1,2, Eleanor Cox3,4, Alison Telford2, Ferenc Mozes5, Gabriela Belsley5, Elizabeth Tunnicliffe5, Michael Brady2, Michael Pavlides5,6,7, Daniel Bulte1, and Susan Francis3,4
1Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom, 2Perspectum Ltd, Oxford, United Kingdom, 3Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 4NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom, 5Oxford Centre for Magnetic Resonance, University of Oxford, Oxford, United Kingdom, 6NIHR Nottingham Biomedical Research Centre, University of Oxford, Oxford, United Kingdom, 7Translational Gastroenterology Unit, University of Oxford, Oxford, United Kingdom

Synopsis

Keywords: Liver, CancerSurvival rates for hepatocellular carcinoma (HCC) are poor, and improved methods for early detection are required. One such method may be the detection of iron sparing in HCC compared to the liver tissue using R2* mapping. We optimised sequences for the assessment of whole liver 3D R2* mapping, and developed a HCC phantom comprising small spheres with a range of R2* values to assess them. Agreement of the phantom R2* with reference values and between vendors, as well as the ability to detect small differences in R2* indicated the sequences have strong potential to detect iron sparing.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract Presentation Video

Keywords