Abstract #2257

Whole-tumor histogram analysis of DWI and DCE-MRI for soft tissue sarcoma: Correlation with HIF-1alpha expression

Xiangwen Li¹, Qing Li², and chen shuang³

¹Huashan hospital Fudan university, Shang hai, China, ²MR Collaborations, Siemens Healthcare Ltd., Shang hai, China, ³Radiology, Huashan hospital Fudan university, Shang hai, China

Synopsis

Keywords: MSK, Diffusion/other diffusion imaging techniquesIn this study, we initially revealed the feasibility of conventional MRI features and whole-tumor histogram features of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced MRI (DCE-MRI) parameters in assessing hypoxia-inducible factor 1-alpha (HIF-1α) expression of soft tissue sarcomas (STS). On this basis, we performed a short-term survival analysis of the study population. The findings suggest that MRI morphological features and histogram features of quantitative parameters help predict higher HIF-1α expression and may significantly predict prognosis in patients with STS.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.