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Abstract #2258

Sex differences in subcutaneous fat thickness and bone marrow fat area and their relationship to BMI and age

Talon Johnson1, Jimin Ren1,2, and Anke Henning1,2
1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 2Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States

Synopsis

Keywords: Bone, Fat, Metabolism, diabetesThis study evaluated the sex factor in affecting fat distribution in bone marrow and subcutaneous tissue in human lower extremity. Bone marrow fat (BMF) was characterized by the cross-sectional area in the fibula bone and subcutaneous fat (SF) was measured by the thickness of SF (SFT) in the periphery of calf muscle. It is found that SFT and BMF are statistically significantly correlated to BMI and age, respectively, in women (n = 43), but not in men (n = 59). For a subgroup of subjects with thinner SFT (<15 mm, n = 87), SFT is negatively correlated to BMF.

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Keywords