Keywords: MSK, Multimodal, Osteosarcoma
In this study, we simultaneously compared the predictive value of ADC, IVIM and semi-quantitative and quantitative DCE-MRI parameters for the efficacy of NACT. We found that D-Bi, D*-Bi, and f-Bi post-NACT and ΔD-Bi had statistical differences between the good response group and the poor response group. ROC curve showed that f-Bi post-NACT had the best performance in all parameters, with AUC of 0.769, sensitivity of 1, and specificity of 0.538. Correlation analysis showed that the efficacy of NACT was negatively correlated with D-Bi, D*-Bi post-NACT and ΔD-Bi, and was significantly positively correlated with f-Bi post-NACT.
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