Abstract #2262

Exercise-stimulated muscle hyperemia: a preliminary investigation with diffusion tensor imaging on calf muscles

Xin Mu¹, Meng Tian², Huahui Xu³, Chang Ni¹, Yanbin Li⁴, Xiangwei Kong¹, Xiaoli Gu³, and Jeff L Zhang¹

¹Vascular and Physiologic Imaging Research (VPIR) Lab, School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, ²School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, ³Department of Radiology, Shanghai Guanghua Hospital of Integrative Medicine, Shanghai, China, ⁴Central Research Institute, UIH Group, United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Skeletal, MuscleDiffusion tensor imaging (DTI) has been shown to be highly sensitive to subtle pathological alterations caused by multiple diseases. Utilizing this capability of DTI, in this study we characterized post-exercise hyperemic responses of calf muscles. We found that multiple DTI measures, including ADC, λ_1-3, and RD, increased significantly in activated muscles, and more than in those in non-activated muscles. Of particular interest was the significant increase in λ₃ and RD of the activated muscle, indicating a relatively higher degree of increase in water diffusion along the cross-section direction of muscle fibers.

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