Abstract #2268

Bone marrow fat composition assessed by fast and simple 1D MRS combined with intermolecular double-quantum coherence on 3.0 T

Jianfeng Bao¹, Xiao Wang², Yuchuan Zhuang³, Liangjie Lin⁴, Yong Zhang², and Jingliang Cheng²

¹Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, zhengzhou, China, ²Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ³Department of Electronic Science, University of Rochester, ROCHESTER, NY, United States, ⁴Philips Healthcare, Beijing, China

Synopsis

Keywords: Bone, Fat, intermolecular double-quantum coherence,fat composition,magnetic resonance spectroscopyUnsaturated fatty acids in the bone marrow may play a critical role in bone metabolism, however, these peaks cannot be well resolved by conventional MRS techniques due to local intensive B0 inhomogeneities. We introduced intermolecular double-quantum coherence to enhance the spectrum resolution on clinical 3.0 T within one minute and more unsaturated peaks can be identified.

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