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Abstract #2277

Construction of disease progression prediction model for PD patients based on DTI data

Amei Chen1, Junxiang Huang2, Xiaofei Huang1, Xiaofang Cheng3, Yongzhou Xu4, and Xinhua Wei1
1Guangzhou First People's Hospital, Guangzhou, China, 2Guangzhou Women and Children's Medical Center, Guangzhou, China, 3The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China, 4Philips Healthcare, Guangzhou, China

Synopsis

Keywords: Parkinson's Disease, Machine Learning/Artificial Intelligence, white matter connectivity, DTI, prediction modelIn this study, the machine learning method was used to establish a prediction model for Parkinson’s disease(PD) progression by using white matter connectivity and clinical information. A total of 123 PD patients were included. White matter network connection analysis and clinical information collection were performed for each patient. The results showed that combined with the white matter connection and clinical features, a good model of PD disease progression was established. White matter network connectivity helps predict PD progression at the individual level.

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