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Abstract #2282

Application of QSM and tSWI in evaluating substantia nigra "swallow tail sign" in the diagnosis of Parkinson's disease

Xiao Feng Shi1, You Min Zhang1, Na Ying He1, Zeng Hui Cheng1, Fu Hua Yan1, and Ewart Mark Haacke2
1Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, shanghai, China, 2SpinTech MRI, Bingham Farms, MI, United States

Synopsis

Keywords: Parkinson's Disease, Parkinson's Disease, swallow tail sign,substantia nigra,MRIThe incidence of Parkinson's disease(PD) is high and the clinical symptoms are diverse making the diagnosis of PD difficult. Loss of the “swallow tail sign” (STS) as an imaging biomarker in the diagnosis of PD. It is of great value in the early diagnosis of PD and the improvement of prognosis. In this study, QSM and tSWI, were used to evaluate the STS of substantia nigra in PD patients. The results show tSWI can better display STS than QSM and its accuracy is higher.

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