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Abstract #2290

Alterations of T1 and proton density values of deep brain nuclei based on synthetic MRI in Parkinson’s disease patients

Jinghan Zhao1, Yinghua Guo2, and Yanwei Miao1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Clinical&Technical Support, Philips Healthcare, Beijing, China

Synopsis

Keywords: Parkinson's Disease, Parkinson's DiseaseThe objective of this study was to explore whether the alterations of T1 and proton density values could reflect the occurrence of Parkinson's disease (PD) and contribute to the prevention and diagnosis of PD. The T1 values of the left caudate nucleus (CN) and the proton density values of all nuclei were significantly reduced in the PD group compared with the control group. The T1 values of the left globus pallidus (GP) and right thalamus (THU) in the PD group were significantly reduced compared with those of the contralateral side.

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