Keywords: Parkinson's Disease, DementiaThe incidence of Parkinson's disease patients combined with dementia increased significantly with the extension of disease course, and increased from 26.3% to 83% at twenty years after diagnosis. This study aims to use diffusion tensor imaging to detect the pattern of white matter damage in long-term PD patients with cognitive impairment, and results indicated that PD patients have diffuse FA decrease of white matter that is correlated with cognitive status.
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