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Abstract #2292

Diagnostic efficacy of combined fractional anisotropy (FA) and mean kurtosis (MK) in detecting the Parkinson disease (PD) model rat

Yanchao Dong1, Yansheng Chen2, and Lanxiang Liu2
1Qinhuangdao Municipal No.1 Hospital, Qinhuandao, China, 2Qinhuangdao Municipal No.1 Hospital, Qinhuangdao, China

Synopsis

Keywords: Parkinson's Disease, Parkinson's Disease, DKIBoth FA and MK in DKI have value in the diagnosis of PD. We here investigated the sensitivity and specificity of FA and MK in the early diagnosis of PD rat model. PD and control group, 20 in each group. The FA, MK and FA+MK in PD group were statistically significantly different from that of the control group (P < 0.01). The Youden’s index of FA+MK value was higher than the two alone. The optimal cut-off FA+MK value was 1.404. The diagnostic efficiency of the FA+MK values were better relative to that two alone in diagnosing PD.

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Keywords