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Abstract #2295

Real-time phase contrast sequences versus conventional phase contrast sequences in cerebral blood flow quantification: an in vivo study

Pan LIU1,2, Heimiri Monnier1, Kimi Piedad Owashi1, Serge Metanbou3, Cyrille Capel4, and Olivier Balédent1,2
1CHIMERE UR 7516, Jules Verne University of Picardy, Amiens, France, 2Medical Image Processing Department, Amiens Picardy University Hospital, Amiens, France, 3Radiology Department, Amiens Picardy University Hospital, Amiens, France, 4Neurosurgery Department, Amiens Picardy University Hospital, Amiens, France

Synopsis

Keywords: Blood vessels, Velocity & Flow, real time phase contrast, phase contrast, cerebral blood flow

Real-time phase contrast sequences (RT-PC) appear to have great potential in clinical applications. However, it is important to validate RT-PC in the quantification of cerebral blood flow prior to its use in clinical applications. In this study, we analyzed RT-PC accuracy by comparing the segmentation area, flow rate and pulsatility index of cerebral vessels obtained from RT-PC and conventional phase contrast sequences. RT-PC with 2×2 mm2 spatial resolution and 75ms/image temporal resolution can accurately quantify cerebral blood flow rate with an error of less than 3%. Higher temporal resolution in RT-PC could improve accuracy in cerebral arterial flow quantification.

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Keywords