Abstract #2303

Magnetic resonance imaging of ultrasound-induced strain fields for discrimination of solid and liquid phases

Ryan Willoughby¹, Henrik Odéen², Jesse Jones³, and Mark Bolding⁴

¹Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, United States, ²Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, ³Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, United States, ⁴Radiology, University of Alabama at Birmingham, Birmingham, AL, United States

Synopsis

Keywords: Blood vessels, Focused UltrasoundFocused ultrasound (FUS) has gained clinical utility as a non-invasive treatment option, but applications to diseases affecting blood vessels in the brain are just now being investigated. MR acoustic radiation force imaging (MR-ARFI) of FUS-induced displacement and strain fields were evaluated along with diffusion imaging as a method of differentiating solid and liquid material inside a tissue-mimicking gelatin phantom. Apparent diffusion coefficient (ADC) performed best as a solid-liquid classifier, and axial displacement performed worst. Normal and shear strain components performed better than displacement measurements alone.

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