Abstract #2313

Development of quantitative vessel analysis platform based on MR angiography to assess reversible cerebral vasoconstriction syndrome

Pei-Hsuan Kuo¹, Shuu-Jiun Wang^2,3,4, Jiing-Feng Lirng^2,5, Shih-Pin Chen^2,3,4, Chia-Hung Wu^2,5, Yu Kuo^2,5, and Chia-Feng Lu¹

¹Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan, ²School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ³Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ⁴Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan, ⁵Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan

Synopsis

Keywords: Blood vessels, VisualizationReversible cerebral vasoconstriction syndrome (RCVS) shows reversible diffuse constriction of the cerebral arteries. Previous studies proposed manual measurement of vasoconstriction. However, the stenosis estimated by comparing the stenosed with proximally normal diameter might result in an underestimate of vasoconstriction for the long-segmental stenosis. Accordingly, we developed a quantitative vessel analysis platform to measure the vasoconstriction rate by comparing vessel diameters between acute and remission MR angiography. Our platform provided objective measures of vasoconstriction and further confirmed that acute RCVS presented not only local vasoconstriction but a large portion of short- and long-segmental vasoconstriction in all artery segments.

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