Abstract #2318

Differentiation of tumor-infiltrated edema and pure vasogenic edema in patients with brain tumors by using a fractional order calculus model

Qinyuan Zhang¹, Jianing Li¹, Yun Su¹, Zhuoheng Yan¹, Zhixuan Hu¹, Weike Zeng¹, Mengzhu Wang², Xu Yan², Jiaji Mao¹, and Jun Shen¹

¹Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China, ²MR Scientific Marketing, Siemens Healthineers Ltd, Guangzhou, China

Synopsis

Keywords: Tumors, Diffusion/other diffusion imaging techniquesA fractional order calculus model (FROC) holds promise in differentiating tumor-infiltrated edema from pure vasogenic edema of brain tumors. This study used a q-space Cartesian grid sampling scheme, diffusion spectrum imaging, in patients with high-grade gliomas, meningiomas and brain metastases to generate FROC-based parameters, including D, β and μ. The μ showed the best individual parameter performance in differentiating tumor-infiltrated edema from pure vasogenic edema.

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