Keywords: Tumors, Blood vesselsGlioblastoma (GBM) is a highly invasive and vascularized primary malignant brain tumor. Glutamine synthetase (GS) could induce vessel sprouting through the improvement of endothelial cell migration in inflammatory diseases. MR vessel size imaging was supposed to visualize angiogenesis potentially in the brain. In the study we research the role of GS on neovascularization in glioma by in vivo vessel size imaging. Our results indicate that the vascular changes mainly occur in the tumor center and significant decreases of microvascular density values in the MSO group compared to the control. GS inhibitor could be a potential drug to treat glioma.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords