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Abstract #2340

T1 and T2 measurements from Neonates at 7 Tesla

Shaihan J Malik1,2,3, Raphael Tomi-Tricot2,4, Philippa Bridgen2,5, Anthony N Price3,5, Megan Quirke5, Daniel V Cromb3, Paul Cawley3,5, Enrico De Vita2,3, Jonathan O’Muircheartaigh3,6, Serena J Counsell3, Sharon Giles2,5, Mary Rutherford3, A. David Edwards3,5,6, Joseph V Hajnal1,2,3, and Tomoki Arichi3,5,6
1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2London Collaborative Ultrahigh field System (LoCUS), King's College London, London, United Kingdom, 3Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 4MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 5Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, 6Centre for Neurodevelopmental Disorders, King's College London, London, United Kingdom

Synopsis

Keywords: Neonatal, RelaxometryT1 and T2 measurements were made in 8 neonates (median age 42+1 weeks) scanned on a 7 Tesla MRI system, using inversion recovery and spin echo methods respectively. The aim of this study is to help to establish expected ranges, to prepare for systematic relaxometry studies, and to identify optimal operating points for imaging neonates at ultra-high field. Region of interest measurements show strong age dependence of T1, and some variation in T2 (particularly in frontal white matter). The measured T1 times are longer than in adults at 7T, and also longer than in neonates imaged on lower field systems.

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