Abstract #2385

A new pulse sequence to selectively probe the signals of γ-aminobutyric acid

Xue Yang¹, Ying Liu², Caixia Fu³, He Wang², Ying-Hua Chu⁴, Da-Xiu Wei¹, and Ye-Feng Yao¹

¹East China Normal University, Shanghai, China, ²Fudan University, Shanghai, China, ³Siemens Shenzhen Magnetic Resonance Ltd., Shanghai, China, ⁴MR Collaboration, Siemens Healthineers Ltd., Shanghai, China

Synopsis

Keywords: Pulse Sequence Design, SpectroscopyA new pulse sequence was developed to selectively probe the signals of γ-aminobutyric acid (GABA). Different with the previous pulse sequences, the signal selectivity of this pulse sequence is achieved by preparation and reconversion of the ¹H spin singlet order (SSO) of GABA. The optimal control method was used in the design of the pulse sequence. By using the developed pulse sequence, the ¹H signals of GABA in human brains were selectively probed.

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